Caesalpinia Crista Linn. Induces protection against DNA and membrane damage

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Caesalpinia Crista Linn. Induces Protection against DNA and Membrane Damage

BACKGROUND Caesalpinia crista is a medicinal herb used to cure various ailments in subtropical and tropical regions of Southeast Asia. OBJECTIVE The objective of this evaluation of C. crista against free radical induced DNA and erythrocyte damage. MATERIALS AND METHODS The profiles of polyphenol and flavonoid were quantified through reversed-phase high-performance liquid chromatography. Fre...

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Traditional Uses, Medicinal and Phytopharmacological Properties of Caesalpinia Crista Linn - an Overview

Caesalpinia Crista of family Fabaceae is a moderately size deciduous tree, growing wild throughout the deciduous forest of India. It is popular in indigenous system of medicine like Ayurveda, Siddha, Unani and Homoeopathy. In the traditional system of medicine various plant parts such as leaves, stem, root, seed and oils are used as anthelmentic, febrifugal, periodic, tonic, and vesicant. They ...

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Hepatoprotective Potential of Caesalpinia crista against Iron-Overload-Induced Liver Toxicity in Mice

The present study was carried out to evaluate the ameliorating effect of Caesalpinia crista Linn. (CCME) extract on iron-overload-induced liver injury. Iron overload was induced by intraperitoneal administration of iron dextran into mice. CCME attenuated the percentage increase in liver iron and serum ferritin levels when compared to control group. CCME also showed a dose-dependent inhibition o...

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Anthracyclines induce DNA damage response-mediated protection against severe sepsis.

Severe sepsis remains a poorly understood systemic inflammatory condition with high mortality rates and limited therapeutic options in addition to organ support measures. Here we show that the clinically approved group of anthracyclines acts therapeutically at a low dose regimen to confer robust protection against severe sepsis in mice. This salutary effect is strictly dependent on the activati...

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Protection against radiation-induced testicular damage in Swiss albino mice by Mentha piperita (Linn.).

The protective effects of Mentha piperita leaf extract against radiation-induced damage in testis of Swiss albino mice have been studied. Animals (Male Swiss albino mice) were given M. piperita leaf extract orally (1 g/kg body weight/day) for three consecutive days before radiation exposure (8 Gy gamma-radiation). Mice were autopsied at 1, 3, 7, 14, and 30 days after irradiation to evaluate the...

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ژورنال

عنوان ژورنال: Pharmacognosy Magazine

سال: 2017

ISSN: 0973-1296

DOI: 10.4103/pm.pm_557_16